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Lab_name_ita

 

Laboratorio di Bioinformatica e

Biologia Sintetica

Percorso

Nicola Melillo


Nicola Melillo

Nicola Melillo, PhD

Mail:

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Phone:

+39-0382-985746

Fax:

+39-0382-525638

Born in Lovere(BG)
 

Main affiliation during PhD studentship

Dipartimento di Ingegneria Industriale e dell'Informazione

Università degli Studi di Pavia

Via Ferrata 5, I-27100 Pavia, Italy

 

 

Positions

August 2021 - Now Pharmacometrics consultant
December 2019 - August 2021 Research associate at Centre for Applied Pharmacokinetic Research (CAPKR), The University of Manchester, Manchester, UK.
2016-2019 PhD student in Bioengineering and Bioinformatics at the University of Pavia.

Academic Degree

2020 PhD in Bioengineering and Bioinformatics at the University of Pavia, Italy
Thesis: Uncertainty and sensitivity analysis for mechanistic models in pharmacometrics.
2016 Laurea Specialistica (MS degree) in Biomedical Engineering at the University of Pavia, Italy
Thesis: Modelli meccanicistici multiscala in Systems Pharmacology: sviluppo di un modello per la descrizione della farmacocinetica dell'Atorvastatina mediante l'integrazione in modelli PBPK di reti metaboliche. Score: 110 out of 110.
2014 Laurea (BS thesis) in Biomedical Engineering at the University of Pavia, Italy
Thesis: Modelli di popolazione in ambito Bayesiano: linee guida per l'implementazione dei principali casi di studio in WinBugs. Score: 110 out of 110.

Research Interests

  • Physiologically based pharmacokinetic (PBPK) modelling
  • Pop-PK/PD models
  • Survival analysis
  • Global sensitivity analysis
  • Absorption models
  • Systems Pharmacology
  • Dynamical models of biological systems
  • Dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) pharmacokinetic modelling

Methodological knowledge

  • Pharmacometrics
  • Developing mathematical models
  • Performing uncertainty and sensitivity analyses
  • Computer programming (Matlab, R, C,...)
  • Statistics
  • Data analysis / machine learning

Publications

Google scholar

Other links

Linkedin
ORCID
Last update 02-08-2021