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Lab_name_ita

 

Laboratorio di Bioinformatica e

Biologia Sintetica

Percorso

Paolo Magni


Paolo Magni

Prof. Paolo Magni, PhD

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Phone:

+39-0382-985511

Fax:

+39-0382-525638

Born in Bormio (SO), on February 1st, 1969
 

Main affiliation

Dipartimento di Ingegneria Industriale e dell'Informazione

Università degli Studi di Pavia

Via Ferrata 5, I-27100 Pavia, Italy

Other affiliations

Centro di Ingegneria Tissutale

Università degli Studi di Pavia

Via Ferrata 5, I-27100 Pavia, Italy

 

 

Current Position

Professor of Biomedical Engineering, Università degli Studi di Pavia, Pavia, Italy

Director of the Bioinformatics, Mathematical Modelling and Synthetic Biology Lab

Academic Degree

1993 Laurea cum laude in Electronics Engineering (course Automatics) at the Università degli Studi di Pavia, Pavia, Italy
1998 PhD in Bioengineering at the Università degli Studi di Pavia, Pavia, Italy

Appointments

2011 - today Professor of Biomedical Engineering at the Università degli Studi di Pavia, Pavia, Italy
2005 - 2011 Assistant professor of Biomedical Engineering at the Università degli Studi di Pavia, Pavia, Italy
2003 - 2004 FIRB researcher at the Università degli Studi di Pavia, Pavia, Italy
1999 - 2003 Researcher at the Università degli Studi di Pavia, Pavia, Italy

Honorary Appointments

1992 - 1993 ERASMUS Student Fellow, Department of Social Science Informatics, University of Amsterdam, The Netherlands

Research Interests

The main research topics are: quantitative modelling of dynamical systems, probabilistic models and Bayesian networks, decision analysis, Markov chain Monte Carlo methods, intelligent data analysis, pharmacokinetic and pharmacodynamic models, population models, telemedicine, bioinformatics, synthetic biology. These methodologies are investigated mainly to solve relevant biological/clinical problems.

Academic Activities

Courses

2011 - today Mathematical modeling of biological systems (including PK/PD models)
2011 - today Bioinformatics and Synthetic Biology
2006 - today Biostatistics
2004 - 2006 Feedback control of dynamical systems
2004 - 2010 Bioinformatics
2003 - 2010 Assistant of Mathematical modeling of biological systems (including PK/PD models)
2001 - 2003 Assistant of Automatic Control

Other Academic Activities

2013 - today President of the Master's degree program in Bioengineering (Referente Laurea Magistrale)
2013 - today Erasmus, Erasmus Placement and International mobility delegate for students of the Master degree in Bioengineering
2013 Member of the group for the Transfer of Technology, Università degli Studi di Pavia, Pavia, Italy
2011 - today Member of the board, Executive committee and Secretary of the PhD in Bioengineering and Bioinformatics, Università degli Studi di Pavia, Pavia, Italy
2009 - 2012 Member of the group for the analysis of national and international university ranking positions and related improving strategies, Università degli Studi di Pavia, Pavia, Italy
2008 - 2011 Member of the Planning committee of the Bioengineering courses, Università degli Studi di Pavia, Pavia, Italy

Scientific Activities

Journal Editorial Boards

2012 - 2013 Member of the Editorial Board of "BMC Bioinformatics NETTAB2012 supplement"
2011 - 2013 Member of the Editorial Board (Associate Editor) of "IEEE Transaction on Biomedical Engineering"
2011 - 2012 Member of the Editorial Board of "BMC Bioinformatics NETTAB2011 supplement"
2007 - 2015 Member of the Editorial Board of "The Open Medical Informatics Journal"

Conference Scientific Committee

2013 - 2014 Member of the scientific committee of the "IV congresso del Gruppo Nazionale di Bioingegneria" (GNB 2014, Pavia, Italy)
2013 - 2016 Member of the scientific committee of BITS (BITS 2013, Udine, Italy; BITS 2014, Roma, Italy; BITS 2015, Milano, Italy; BITS 2016, Salerno, Italy)
2012 - today Member of the board of the PAGE
2011 - 2012 Member of the scientific board of the NETTAB 2011 and 2012

Organization of Scientific Events

2015 - 2016 Organizer of the Lake Como School on "Quantitative translational approaches in oncology drug" (2016, Como, Italy)
2015 - 2016 Organizer of the "5th public DDMoRe course:Model-informed Drug Development in Oncology (Advanced)" (2016, Pavia, Italy)
2014 - 2015 Organizer of the "1st public DDMoRe course:Model-informed Drug Development in Oncology (Beginners)" (2015, Berlin, Germany)
2013 - 2014 Organizer and co-chair of the "IV congresso del Gruppo Nazionale di Bioingegneria" (GNB 2014, Pavia, Italy)
2011 - 2014 Member of the organizing committee of the international school on "Analysis of Longitudinal Data in Oncology" (ALDO 2012-2013, Grenoble, France; ALDO 2014, Lyon, France)
2011 - 2012 Member of the local organizing committee of the "Population Approach Group in Europe" (PAGE 2012, Venice, Italy)
2010 Member of the organizing committee of the XXIX Bioingeneering National Group school entitled: "Synthetic Biology"
2000 Deconvolution Methods in Pharmacokinetic Systems Analysis, an invited session of World Congress on Medical Physics and Biomedical Engineering, Chicago

International and National Organizations, Awards

1998 - today Member of the Bioengineering National Group (GNB)
2008 - today Member of the Italian Bioinformatics Association
2013 The title "Spin-off accademico di eccellenza" is given to Biomeris s.r.l.
2011 Gold medal to the iGEM (International Genetically Engineered Machine) competition with the project "Ctrl+E. - Signaling is nothing without control"
2010 Gold medal to the iGEM (International Genetically Engineered Machine) competition with the project "ProteInProgess"
2009 Gold medal from the city of Pavia and the title of citizen who has contributed to augment prestigious of the whole Pavia community for his teaching and research activities (Benemerenza di S. Siro)
2009 Gold medal and special prize (best food or energy project) to the iGEM (International Genetically Engineered Machine) competition with the project "Ethanol whey not?"
2008 Silver medal to the iGEM (International Genetically Engineered Machine) competition with the project "Engineering E. coli to multiplex and demultiplex signals"

Main research grants

EU Projects

2011 - 2016 DDMoRe: Drug Disease Model Resources (Principal investigator, WP leader)
2000 - 2002 M2DM: Multi-access System for the Management of Diabetic Mellitus Patients
1999 - 2000 Bayesian Knowledge Extractor (BaKE) - Esprit 29105

National Projects

MIUR - PRIN
2005 - 2007 Modelli dinamici dell'espressione genica e proteica in cellule progenitrici endoteliali nell'evoluzione del diabete
2004 - 2006 Analisi intelligente dei dati di monitoraggio di emodialisi per il miglioramento dei processi di cura
2003 - 2005 Modelli dinamici dell'espressione genica da dati di microarray
2000 - 2002 Stima di parametri non accessibili in sistemi fisiologici
2000 - 2002 Analisi, visualizzazione di informazioni ed interrogazioni visuali di basi di dati per il monitoraggio clinico
MIUR - FIRB
2007 - 2013 ITALBIONET - Rete Italiana di Bioinformatica
2006 - 2009 Accordi Italia-USA. Teoria dell'Apprendimento e Applicazioni
2002 - 2005 Le tecnologie dell'informazione e della comunicazione per la gestione dei processi di prevenzione, cura e riabilitazione
MIUR - Giovani Ricercatori
1999 Stima Bayesiana di parametri di popolazione di modelli metabolici (Principal investigator)
Ministero della Sanità - Ricerca Finalizzata
1999 - 2002 Teleassistenza per pazienti in dialisi peritoneale
Università degli Studi di Pavia
2008 Progettazione ed implementazione di un circuito genetico standardizzato per implementare una funzione logica nel batterio E. coli (Fondo di Ateneo per la Ricerca) (Principal investigator)
2006 Metodi bayesiani per l'identificazione di modelli di popolazione per l'analisi quantitativa di sistemi endocrino-metabolici (Fondo di Ateneo per la Ricerca) (Principal investigator)
1998-1999 Prototipo di un data-warehouse di Ateneo (Progetto finanziato dal Nucleo di Valutazione) (Principal investigator)

Company/private institutions

2016 - 2017 PKPD modelling on oncology (Menarini Ricerche) (Principal investigator)
2016 - 2017 WB-PBPK modelling (Chiesi Farmaceutici) (Principal investigator)
2016 - 2019 Conversion of industrial bio-waste into biofuels and bioproducts through synthetic biology (Fondazione Cariplo) (Principal investigator)
2006 - 2009 Sviluppo di metodologie e tool bioinformatici per lo studio dell'effetto di farmaci antitumorali a livello cellulare (Nerviano Medical Sciences) (Principal investigator)
2007 - 2009 Dose escalation e valutazione di studi clinici (GSK - GlaxoSmithKline)
2006 - 2007 Sviluppo di metodologie e tool software per l'analisi di dati FRET e FRAP (San Raffaele Scientific Institute, Milano) (Principal investigator)
2004 - 2008 Sviluppo di modelli e analisi dati relativi alla valutazione di farmaci (Pharmacia and Nerviano Medical Sciences)
2002 - 2003 Modelli nonlineari di popolazione a effetti misti per studi preclinici di efficacia e tossicità. Attività di sviluppo di modelli e analisi dei dati relative alla valutazione di un nuovo farmaco antitumorale dato in combinazione (Pharmacia)
2001 - 2002 Modelli misti nonlineari di popolazione applicati alla farmacocinetica e farmacodinamica. Metodi farmacocinetici e farmacodinamici applicati a farmaci antitumorali (Pharmacia)
1999 - 2001 Identificabilità e progetto ottimo per modelli misti non lineari e simulazione di studi clinici e preclinici (Pharmacia)

Other Activities

2016 - today Founder of DDMoRe foundation and member of the governing board from the beginning
2016 - today Founder of enGenome s.r.l. (a spin-off of the Università degli Studi di Pavia) and member of the governing board since its foundation
2012 - today Founder of Biomeris s.r.l. (a spin-off of the Università degli Studi di Pavia) and member of the governing board since its foundation
2012 Member of the board of the Polo tecnologico (Innovation Park) of Pavia

Publications

Author of more than 75 publications on international peer reviewed journals and of more than 180 publications in proceedings of international conferences

Google Scholar publication list

Scopus publication list

Last update 20-11-2016