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Prof. Paolo Magni, PhD
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Mail:
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Questo indirizzo email è protetto dagli spambots. E' necessario abilitare JavaScript per vederlo.
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Phone:
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+39-0382-985511
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Fax:
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+39-0382-422583
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Current Position
Full professor of Biomedical Engineering, Università degli Studi di Pavia, Pavia, Italy
Director of the Bioinformatics, Mathematical Modelling and Synthetic Biology Lab
Academic Degree
| 1993 |
Laurea cum laude in Electronics Engineering (course Automatics) at the Università degli Studi di Pavia, Pavia, Italy |
| 1998 |
PhD in Bioengineering at the Università degli Studi di Pavia, Pavia, Italy |
Appointments
| 2017 - today |
Full professor of Biomedical Engineering at the Università degli Studi di Pavia, Pavia, Italy |
| 2011 - 2017 |
Professor of Biomedical Engineering at the Università degli Studi di Pavia, Pavia, Italy |
| 2005 - 2011 |
Assistant professor of Biomedical Engineering at the Università degli Studi di Pavia, Pavia, Italy |
| 2003 - 2004 |
FIRB researcher at the Università degli Studi di Pavia, Pavia, Italy |
| 1999 - 2003 |
Researcher at the Università degli Studi di Pavia, Pavia, Italy |
Honorary Appointments
| 1992 - 1993 |
ERASMUS Student Fellow, Department of Social Science Informatics, University of Amsterdam, The Netherlands |
Research Interests
| The main research topics are: quantitative modeling of dynamic systems; Bayesian estimation and Markov chain Monte Carlo methods; intelligent data analysis using probabilistic, machine learning and AI techniques; decision making; biostatistics; pharmacometrics (including pharmacokinetics and pharmacodynamics models, population models), modeling and simulation of metabolic systems, bioinformatics and synthetic biology. These methodologies are investigated mainly to solve relevant biological/clinical problems. |
Academic Activities
Courses
Other Academic Activities
| 2018 - today |
Chair of the Bachelor degree program in Bioengineering (Referente Corso di Laurea) |
| 2018 - today |
Erasmus, Erasmus Placement and International mobility delegate for students of the Bachelor degree in Bioengineering |
| 2013 - today |
Chair of the Master degree program in Bioengineering (Referente corso di Laurea Magistrale) |
| 2013 - today |
Erasmus, Erasmus Placement and International mobility delegate for students of the Master degree in Bioengineering |
| 2013 |
Member of the group for the Transfer of Technology, Università degli Studi di Pavia, Pavia, Italy |
| 2011 - today |
Member of the board, Executive committee and Vice-coordinator of the PhD in Bioengineering, Bioinformatics and Health Technologies, Università degli Studi di Pavia, Pavia, Italy |
| 2009 - 2012 |
Member of the group for the analysis of national and international university ranking positions and related improving strategies, Università degli Studi di Pavia, Pavia, Italy |
| 2008 - 2011 |
Member of the Planning committee of the Bioengineering courses, Università degli Studi di Pavia, Pavia, Italy |
Scientific Activities
Journal Editorial Boards
| 2021 - today |
Member of the Editorial Board of "Journal of Pharmacokinetics and Pharmacodynamics" |
| 2012 - 2013 |
Member of the Editorial Board of "BMC Bioinformatics NETTAB2012 supplement" |
| 2011 - 2013 |
Member of the Editorial Board (Associate Editor) of "IEEE Transaction on Biomedical Engineering" |
| 2011 - 2012 |
Member of the Editorial Board of "BMC Bioinformatics NETTAB2011 supplement" |
| 2007 - 2015 |
Member of the Editorial Board of "The Open Medical Informatics Journal" |
Conference Scientific Committee
| 2013 - 2014 |
Member of the scientific committee of the "IV congresso del Gruppo Nazionale di Bioingegneria" (GNB 2014, Pavia, Italy) |
| 2013 - 2018 |
Member of the scientific committee of BITS (BITS 2013, Udine; BITS 2014, Roma; BITS 2015, Milano; BITS 2016, Salerno; BITS 2017, Cagliari; BITS 2018, Torino) |
| 2012 - today |
Member of the board of the PAGE |
| 2011 - 2012 |
Member of the scientific board of the NETTAB 2011 and 2012 |
Organization of Scientific Events
| 2015 - 2016 |
Organizer of the Lake Como School on "Quantitative translational approaches in oncology drug" (2016, Como, Italy) |
| 2015 - 2016 |
Organizer of the "5th public DDMoRe course:Model-informed Drug Development in Oncology (Advanced)" (2016, Pavia, Italy) |
| 2014 - 2015 |
Organizer of the "1st public DDMoRe course:Model-informed Drug Development in Oncology (Beginners)" (2015, Berlin, Germany) |
| 2013 - 2014 |
Organizer and co-chair of the "IV congresso del Gruppo Nazionale di Bioingegneria" (GNB 2014, Pavia, Italy) |
| 2011 - 2014 |
Member of the organizing committee of the international school on "Analysis of Longitudinal Data in Oncology" (ALDO 2012-2013, Grenoble, France; ALDO 2014, Lyon, France) |
| 2011 - 2012 |
Member of the local organizing committee of the "Population Approach Group in Europe" (PAGE 2012, Venice, Italy) |
| 2010 |
Member of the organizing committee of the XXIX Bioingeneering National Group school entitled: "Synthetic Biology" |
| 2000 |
Deconvolution Methods in Pharmacokinetic Systems Analysis, an invited session of World Congress on Medical Physics and Biomedical Engineering, Chicago |
International and National Organizations, Awards
| 1998 - today |
Member of the Bioengineering National Group (GNB) |
| 2008 - today |
Member of the Italian Bioinformatics Association |
| 2017 |
"Novartis Oncology Award" is given to enGenome s.r.l at the BioInItaly Investment Forum & Intesa Sanpaolo StartUp Initiative |
| 2013 |
The title "Spin-off accademico di eccellenza" is given to Biomeris s.r.l. |
| 2011 |
Gold medal to the iGEM (International Genetically Engineered Machine) competition with the project "Ctrl+E. - Signaling is nothing without control" |
| 2010 |
Gold medal to the iGEM (International Genetically Engineered Machine) competition with the project "ProteInProgess" |
| 2009 |
Gold medal from the city of Pavia and the title of citizen who has contributed to augment prestigious of the whole Pavia community for his teaching and research activities (Benemerenza di S. Siro) |
| 2009 |
Gold medal and special prize (best food or energy project) to the iGEM (International Genetically Engineered Machine) competition with the project "Ethanol whey not?" |
| 2008 |
Silver medal to the iGEM (International Genetically Engineered Machine) competition with the project "Engineering E. coli to multiplex and demultiplex signals" |
Main research grants
EU Projects
National Projects
MIUR - PNRR
| 2022 - 2025 |
Nodes- Spoke 2 - Green technologies and sustainable industry |
| 2022 - 2025 |
CENTRO NAZIONALE "HPC, big data e quantum computing" - Spoke 8 |
MIUR - PRIN
| 2005 - 2007 |
Modelli dinamici dell'espressione genica e proteica in cellule progenitrici endoteliali nell'evoluzione del diabete |
| 2004 - 2006 |
Analisi intelligente dei dati di monitoraggio di emodialisi per il miglioramento dei processi di cura |
| 2003 - 2005 |
Modelli dinamici dell'espressione genica da dati di microarray |
| 2000 - 2002 |
Stima di parametri non accessibili in sistemi fisiologici |
| 2000 - 2002 |
Analisi, visualizzazione di informazioni ed interrogazioni visuali di basi di dati per il monitoraggio clinico |
MIUR - FIRB
| 2007 - 2013 |
ITALBIONET - Rete Italiana di Bioinformatica |
| 2006 - 2009 |
Accordi Italia-USA. Teoria dell'Apprendimento e Applicazioni |
| 2002 - 2005 |
Le tecnologie dell'informazione e della comunicazione per la gestione dei processi di prevenzione, cura e riabilitazione |
MIUR - Giovani Ricercatori
| 1999 |
Stima Bayesiana di parametri di popolazione di modelli metabolici (Principal investigator) |
Ministero della Sanità - Ricerca Finalizzata
| 1999 - 2002 |
Teleassistenza per pazienti in dialisi peritoneale |
Regione Lombardia
| 2020 - 2022 |
Circular Economy for water and energy (Hub ricerca e innovazione) |
Università degli Studi di Pavia
| 2008 |
Progettazione ed implementazione di un circuito genetico standardizzato per implementare una funzione logica nel batterio E. coli (Fondo di Ateneo per la Ricerca) (Principal investigator) |
| 2006 |
Metodi bayesiani per l'identificazione di modelli di popolazione per l'analisi quantitativa di sistemi endocrino-metabolici (Fondo di Ateneo per la Ricerca) (Principal investigator) |
| 1998-1999 |
Prototipo di un data-warehouse di Ateneo (Progetto finanziato dal Nucleo di Valutazione) (Principal investigator) |
Company/private institutions
| 2023 - 2024 |
Combining Reinforcement Learning and PK-PD models to personalize drug therapy (Ares Trading S.A.-an affiliate of Merck) (Principal investigator) |
| 2023 - 2024 |
PKPD modelling on oncology (Menarini Ricerche) (Principal investigator) |
| 2021 |
Simulation of a Phase III study (Italfarmaco) (Principal investigator) |
| 2021 |
PK/PD modeling of pediatric and adult studies (Janssen) (Principal investigator) |
| 2021 |
Pharmacometrics training (Angelini spa) (Instructor) |
| 2021 - 2022 |
PKPD modelling on oncology (Menarini Ricerche) (Principal investigator) |
| 2020 |
Support to drug registration procedure for pediatric populations (Angelini spa) (Principal investigator) |
| 2019 - 2020 |
PKPD modelling to support drug development (Italfarmaco) (Principal investigator) |
| 2019 - 2020 |
PKPD modelling on oncology (Menarini Ricerche) (Principal investigator) |
| 2018 - 2021 |
Bioinformatics support to several projects (AUSL Reggio Emilia) (Principal investigator) |
| 2018 - 2021 |
Sustainable bioconversion of lactose into ethanol: field testing of a demonstration plant to close the valorization cycle of dairy waste (Fondazione Cariplo) (Principal investigator) |
| 2016 - 2017 |
PKPD modelling on oncology (Menarini Ricerche) (Principal investigator) |
| 2016 - 2019 |
WB-PBPK modelling (Chiesi Farmaceutici) (Principal investigator) |
| 2016 - 2020 |
Conversion of industrial bio-waste into biofuels and bioproducts through synthetic biology (Fondazione Cariplo) (Principal investigator) |
| 2006 - 2009 |
Sviluppo di metodologie e tool bioinformatici per lo studio dell'effetto di farmaci antitumorali a livello cellulare (Nerviano Medical Sciences) (Principal investigator) |
| 2007 - 2009 |
Dose escalation e valutazione di studi clinici (GSK - GlaxoSmithKline) |
| 2006 - 2007 |
Sviluppo di metodologie e tool software per l'analisi di dati FRET e FRAP (San Raffaele Scientific Institute, Milano) (Principal investigator) |
| 2004 - 2008 |
Sviluppo di modelli e analisi dati relativi alla valutazione di farmaci (Pharmacia and Nerviano Medical Sciences) |
| 2002 - 2003 |
Modelli nonlineari di popolazione a effetti misti per studi preclinici di efficacia e tossicità. Attività di sviluppo di modelli e analisi dei dati relative alla valutazione di un nuovo farmaco antitumorale dato in combinazione (Pharmacia) |
| 2001 - 2002 |
Modelli misti nonlineari di popolazione applicati alla farmacocinetica e farmacodinamica. Metodi farmacocinetici e farmacodinamici applicati a farmaci antitumorali (Pharmacia) |
| 1999 - 2001 |
Identificabilità e progetto ottimo per modelli misti non lineari e simulazione di studi clinici e preclinici (Pharmacia) |
Other Activities
| 2016 - 2022 |
Founder of DDMoRe foundation and member of the governing board from the beginning |
| 2016 - today |
Founder of enGenome s.r.l. (a spin-off of the Università degli Studi di Pavia) and member of the governing board since its foundation |
| 2012 - today |
Founder of Biomeris s.r.l. (a spin-off of the Università degli Studi di Pavia) and member of the governing board since its foundation |
| 2012 |
Member of the board of the Polo tecnologico (Innovation Park) of Pavia |
Publications
Author of more than 120 publications on international peer reviewed journals and of more than 400 publications in proceedings of international conferences
Google Scholar publication list
Scopus publication list
Last update 03-06-2024
Dipartimento di Ingegneria