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Massimo Bellato
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Mail:
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This email address is being protected from spambots. You need JavaScript enabled to view it.
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Phone:
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+39-0382-985746
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Fax:
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+39-0382-422583
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Current Position
Research Fellow, University of Padova, Italy
Academic Degree
| 2012 |
Laurea (BS thesis) in Biomedical Engineering at the University of Padova, Italy
Thesis: Il sistema Bose Electroforce per la caratterizzazione del comportamento a trazione di pericardio bovino e porcino. Score: 96 out of 110. |
| 2015 |
Laurea Specialistica (MS degree) in Bioengineering at the University of Pavia, Italy
Thesis: Progettazione bottom-up di sistemi biologici: debug di circuiti genetici interconnessi mediante approcci in-vivo ed in-silico. Score: 109 out of 110. |
| 2018 |
Dottorato (PhD) in Bioengineering and Bioinformatics at the University of Pavia, Italy
Thesis: Overcoming Metabolic Burden in Synthetic Biology: A CRISPR-interference Approach. |
Appointments
| 2015-2018 |
PhD Student in Bioengineering and Bioinformatics, BMS Laboratory and Centre for Health Technologies - CHT, University of Pavia, Italy |
| 2018-2020 |
Research Fellow, BMS Laboratory and Centre for Health Technologies - CHT, University of Pavia, Italy |
| 2020 - today |
Research Fellow, Dept. of Information Engineering and Dept. of Molecular medicine, University of Padova, Italy |
Honorary appointments
Sep.2017 -
Feb. 2018 |
Visiting researcher, Del Vecchio Laboratory, Synthetic Biology Centre - SBC, Massachusetts Institute of Technology, USA |
Research Interests
- Microbiome Engineering, in particular:
- Development of genetic modules for therapeutic actions in microbiota
- Treatment of Clostridium difficile infection through synthetic biology based approaches
- Study of quorum sensing mechanisms in bacterial pathogens
- Synthetic Biology in bacteria, in particular:
- Rational design of synthetic genetic circuits;
- Mathematical modeling of biological context dependencies;
- Genetic feedback controllers;
- CRISPR technology and applications, in particular:
- CRISPR-interference characterization and exploitation for reduced burden circuit design;
- CRISPR-interference competition
- Design of CRISPRi-based genetic controllers
- Microbiome engineering;
- Cross-kingdom gene regulation.
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Academic Activities
Courses
| 2016/19 |
Tutor of Biostatistic course - University of Pavia
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| 2016/17 |
Tutor of Math course for newly-registered in Egnineering
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Others
| 2016 |
Co-supervisor of the thesis: "Modellizzazione matematica e studio degli effetti del carico metabolico in circuiti genetici interconnessi in E. coli " by Alberto Serra, Bioengineering Master's Degree
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| 2016 |
Co-supervisor of the thesis: "Investigating mechanistic models to describe the effect of cell burden on gene expression in the Lux system " by Elena Arrigotti, Bioengineering Master's Degree
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| 2018 |
Co-supervisor of the thesis: "Bypassing metabolic burden in E. coli: characterization and standardization of a novel CRISPR interference toolbox for rational design in Synthetic Biology " by Elia Salibi, Molecular Biology and Genetics Master's Degree
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| 2018 |
Co-supervisor of the thesis: "Approcci per l'ottimizzazione della regolazione genica mediante CRISPR interference in E. coli " by Angelica Frusteri Chiacchiera, Advanced Biotechnology Master's Degree
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Scientific activities
International and National Organizations, Awards
| 2015 |
"Gruppo Nazionale di Bioingegneria" (15th edition) award for the Master Thesis |
Publications
Google Scholar publication list
Last update 08-07-2016
Department of Electrical, Computer and Biomedical Engineering