Logo_BMS

 

Lab_name_en

Bioinformatics,

Mathematical Modelling and

Synthetic Biology Lab

Logo_UniPv_en

Logo UniPVDepartment of Electrical, Computer and Biomedical Engineering

Percorso

Roberta Bartolucci


Roberta Bartolucci

Roberta Bartolucci, PhD student

Mail:

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Phone:

+39-0382-985746

Fax:

+39-0382-525638
Born in Verbania (VB), on June 29th, 1992

Main affiliation

Dipartimento di Ingegneria Industriale e dell'Informazione

Università degli Studi di Pavia

Via Ferrata 5, I-27100 Pavia, Italy

 

 

Current Position

2nd year PhD Student at University of Pavia, Italy

Academic Degree

2014 Laurea (BS degree) in Biomedical Engineering at the University of Pavia, Italy
Thesis: "Modellistica e controllo di un robot mobile realizzato con Lego Mindstorms". Score: 99/110
2016 Laurea Specialistica (MS degree) in Biomedical Engineering at the University of Pavia, Italy
Thesis: "Sviluppo di un modello PBPK per lo studio della farmacocinetica dell'Azatioprina nel ratto e possibile traslazione all'uomo". Score: 110/110

Research Interests

  • Optimal design for pediatric clinical trials
  • population models with Bayesian estimation techniques
  • Tumor-Growth Inibition Models with anticancer drugs given in combination
  • Development of physiologically-based pharmacokinetics (PBPK) models
  • Drug-Drug Interactions (DDI) analysis
  • Inter-species scaling and First In Human (FIH) problems

Academic activities

Conferences Participation

2018 ACOP9 meeting, San Diego, California, USA
2018 PAGE meeting, Montreux, Switzerland
2018 Sesto Congresso Nazionale di Bioingegneria, Milano, Italy
2017 PAGE meeting, Budapest,Hungary

courses

2017-2018 Tutor of: Biostatistics - University of Pavia
2017-2018 Tutor of: Models for biological systems - University of Pavia

Thesis Supervising

  • Raul Eugen Ciuche. Analisi non compartimentale per la Nifedipina tramite il software WinNonlin. Bachelor degree in Bioengineering, University of Pavia, 2016-2017
  • Francesco Pozzoni. Implementazione di modelli per la generazione di popolazioni virtuali: confronto sul caso del topiramato. Bachelor degree in Bioengineering, University of Pavia, 2017-2018

Publication

Proceedings of international conferences

  • Roberta Bartolucci, Nicola Melillo, Paolo Magni. Whole-body PBPK model for a translational study of Azathioprine pharmacokinetics. Proceedings of the 2018 ACOP9 meeting, Oct 7-10, San Diego, California, USA.
  • Roberta Bartolucci, Nicola Melillo, Paolo Magni. Development of a PBPK model for the study of Azathioprine pharmacokinetics in rats and translation in humans. Proceedings of the 2018 GNB conference, June 25-27, Milano
  • Roberta Bartolucci, Nicola Melillo, Paolo Magni. A PBPK model for the study of Azathioprine pharmacokinetics in rats and prediction in humans. Proceedings of the 2018 PAGE meeting, May 29 - June 1, Montreux, Switzerland
  • Roberta Bartolucci, Silvia Maria Lavezzi, Elena Maria Tosca, Nicola Melillo, Silvia Grandoni, Elisa Borella, Lorenzo Pasotti, Giuseppe De Nicolao, Paolo Magni. Evaluation of software tools for Bayesian estimation on population models: an update based on current software versions. Proceedings of the 2018 PAGE meeting, May 29 - June 1, Montreux, Switzerland
Last update 26-09-2018